Human Platelet Lysate (hPL) is a xeno-free alternative to FBS. It is a well promising source of bioactive substances like growth factors (e.g. bFGF, TGF-ß, IGF-1) not only for in vivo wound healing and tissue repair, but also for the expansion of human cells in culture.
HPL is able to promote Mesenchymal stem cell (MSC) expansion, to decrease the time required to reach confluence and to increase CFU-F size, as compared to the FBS medium. HPL form PAN-Biotech is derived from volunteer donors. The single sample collections are taken from human, healthy donors in certified donation institutions in Europe. The collection of blood follows the EU standards (Directive 2002/98/ EC – quality and safety standards for the collection, testing, processing, storage and distribution of human blood and blood components).
According to the EU standards the donors were tested for the following infection parameters: HBsAg, HBV DNA, anti- HCV, HCV RNA, anti-HIV, HIV RNA and Lues serology.